You can give your manager the chance to make a modification, but you should be mentally prepared to leave before you do that. They probably won't fire you just for explaining some interpersonal difficulties, but it will mark you as a dissatisfied employee and fundamentally change your relationship with the company. You'll be at the top of the list for layoffs or other adverse action.

Don't go into this with any expectation that anything will get fixed. Most likely, the manager will take your concerns to your co-workers and tell them to fly right, they'll make a token effort for a couple of weeks, and it'll go right back to the way it was after that.