You might want to take a look at the 'Stylish'[1] extension if you often feel like modifying the CSS on sites you visit.
Personally I got used to changing the zoom all the time, with the amount of sites that solve the DPI problem by multiplying the size of everything by 2.
[1] Firefox: https://addons.mozilla.org/en-us/firefox/addon/stylish/
Chrome: https://chrome.google.com/webstore/detail/stylish/fjnbnpbmke...
Find styles: https://userstyles.org/