I've been using hotloading css, react and redux for the past few months and it's an amazing experience. It enables you to iterate quickly and see changes immediately. (Admittedly, as a project grows, there's a small delay between saving and seeing the change. I'm not sure if it's avoidable or not... But it's still much faster than having to do a full-page reload.)
[0] https://gaearon.github.io/react-hot-loader/