* Security : customers acccounts leaked, identities stolen, bank account depleted
* Undetected data corruption : customers' data is corrupted and it has seeped into the backup stream, even the off-site one, and that is corrupted as well now.
* Rarely occurring simingly random concurrency related bugs that manifest themselves once a month or longer.
* Time : making assumptions about it, dealing with it distributed systems etc. Nobody thinks about it until it stops working or systems' time gets snapped back somehow.