All of humanity's scientific progress has been a step-by-step widening of the circle of our knowledge into that vast universe of the unknown. There is certainly a point in acknowledging it, acknowledging its vastness in comparison to what we actually know, and looking for the next tiny pebble we can chip out of that wall of ignorance.
That's just my opinion of course.
Of course you can "prove"/"disprove" them, otherwise they wouldn't be discussed by scientists but by philosophers or theologians. For theories to be different, there must be an experiment that in principle could be done, for which each of them predicts different result. If we get around doing that expriment, we'll learn which theory is the right model.
This is an universal principle of science and applies at every level - both fundamentals and macro/practical.