Whole grain bread is the foundation of western civilization for a reason. It contains a huge assortment of what the human body needs as a single food source. Combined with a little meat and a little fruit and a human go go from a child to live a long and healthy life eating nothing else. However, you can also make a healthy diet by completely avoiding it. A large part of a healthy diet is variety and while that can be a pain in our modern society blaming any single highly refined food as horrible while ignoring the other components of your diet is missing a large part of the story.
The less verity in a persons diet the closer to perfection what they do eat needs to be. When you consider the quantity of fructose in the average American diet of course there is a problem, but mainly because of what it replaces and not what it is. If you burned 4k calories a day and drink 1k worth of sucrose water you can still have a healthy if unusual diet. However, when you are only consuming 2k worth of calories a day 50% of which provides zero nutrition your body is probably missing out on important things.