Unless you're using statistics measuring effects per capita of the population using each individual substance, the alcohol vs other drugs discussion is a arguably pretty massive turn into "my personal rant" territory. There is a ton of bad data in this area based on decades of willingness to believe the absolute worst results are 100% correct. More scrutiny has begun to reveal the social impact of particular drugs is much more nuanced than previously considered.

Stopping to re-evaluate the data leads to better outcomes. Such as the correlation between decriminalisation of canabis and a reduction in drug related crime. The same as we saw with the repeal of prohibition and the reduction in the need to bootleg for something society broadly decided was "fine". If the social contract between government and the governed breaks down so far that you have public wilful disobedience of a law, then it's unlikely that you can imprison enough people for breaking that law to ever stop the inevitable change to those laws.