-I think Android apps will kick off in a much bigger way this year with more people getting their hands on phones supporting the OS. It's still early enough to get into IMO.
-On this page Veera suggested the Semantic Web, and while I have big hopes for the Semantic Web (I should, I blog[ged] about it), it's just not going to mature into what I think you're looking for in the amount of time you're looking for.
-Tichy suggested Data Mining, which I'm getting very into as of late, so maybe I'm not in the best position to give an impartial opinion but I think that will be taking off more. :)
Edit: fixed linebreaks