No, backwards: the C10k techniques are the solution to the problem "how do I achieve my performance and scaling goals given the characteristics of the OS, languages, tools available to me today?". The current thread (sic) is asking the question "if we can change the language, tools (perhaps the OS too), what's the best approach?".

And: I have to counterbalance the assertion that Node.js is in any way good for anything besides "I need to code in JS, but not in the browser". I'd rather use VAX assembler and the $QIO syscall, typing on a VT100.