I just tried to develop a website with SBCL and Hunchentoot, and it works relatively well for small examples. There's pretty good MySQL support, and it's all pretty fast. I couldn't figure out how to get a long-running SBCL process to keep even on memory usage. I saw a talk from a guy who works at ITA software [1] where he said they blow away their SBCL instances and restart them on regular intervals, so maybe it's just not possible!
To anyone who is serious about developing a Lisp website, I'd spend a lot of time up-front evaluating different Lisps
[1] I can't find this talk anymore :<