There are still a few one-word domains left in the .com TLD (e.g. naziisms.com, regularizing.com, castigators.com). I myself registered one earlier this summer.
"Certainly there are some unfortunate connotations with our name, but we feel that the advantage of having a memorable, one-word dot-com domain name is worth it." - Bob Q. Startup, Founder and CEO of Naziisms, Inc.
(BTW, after clicking through random domains 50 or so times, I had some of them come up 3 times, which makes me think that there are more like 50-100 untaken .com domains than the 1.4K they say.)