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wk_end

6,575 karma · joined October 10, 2013

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wk_end··on Caffeinated and decaffeinated coffee lower stress, depression and impulsivity
The sentence immediately before the one you quoted notes that there was a group of non-coffee drinkers in the study, and the sentence immediately after states that both groups experienced the positive effects.
wk_end··on U.S. allows Anthropic to release Mythos AI to ‘trusted’ US organizations
At least in part that's because they've stopped legislating. The executive now basically just does whatever it wants.
wk_end··on F* file system – file search that reads SSD directly bypassing OS kernel
Saw the name and was disappointed that this wasn't some kind of verified file system written in the F* programming language (https://fstar-lang.org).

I don't think I'd ever trust or use this, but still, good job OP :)

wk_end··on Rent collections are down in New York
We shouldn't talk about "objective best" without pinning down what that means. I can only really imagine it in a sort of Aristotelian sense - a city could be the best city because it most fully embodies the notion of what it means to be city (as opposed to a more rural or suburban area): a usually cosmopolitan agglomeration of people where the density/economies of scale/competition create an environment that allows art, culture, entertainment, public services, etc. to flourish. In that particular sense I think NYC is the clear best city in the country, no competition, with maybe Chicago being a somewhat distant runner-up. In that mode of thinking it's arguably the best city in the world, actually.

Now, that said: when I lived in the US I (mostly) preferred living in Seattle over NYC for the weather, natural beauty, and more laid-back vibe...subjectively Seattle was better for me, but I still don't have an issue with saying NYC is "objectively" a better city than Seattle.

wk_end··on Noam Shazeer Joins OpenAI
I actually don't know how much of that's especially true where doctors are involved. We as a society strictly regulate who can call themselves a doctor and the credentials that are required to do so, and then in doing so entrust them as a class to be reliable arbiters of what constitutes what's medically necessary, how public medical funds should be spent (which, even if that's something activists agitate for, is still a separate issue), and so on. We also entrust them to help monitor how parents are treating their children.

Anyway, to double back once, it actually doesn't really "assume it's a medically necessary procedure"; we can soften it to something like a "medically desired procedure" and the point in fact still stands that Shazeer's wording - which really should be the point here, not re-enacting the tired trans healthcare debate - is deliberately incendiary and manipulative. Broadly, no one is advocating for parents to be sterilizing their children as an end to itself, so it shouldn't be characterized as such.

wk_end··on Noam Shazeer Joins OpenAI
What's medically necessary is for a person and their own doctors to decide on, not for you or some AI engineer or anyone else to disagree about.
wk_end··on Noam Shazeer Joins OpenAI
The "sterilizing children" is how anti-trans activists talk about giving trans children gender-affirming care. Framing it this way makes it sound monstrous rather than an unfortunate side-effect of a medically necessary procedure, in the same way that characterizing a surgeon who performs hysterectomies for women with ovarian cancer as "a doctor who goes around sterilizing women" would be painting them in an unfair light.

And of course he's not directly accusing his coworkers of "sterilizing children", but he's 1) using language that compares politically sensitive health services that many of his coworkers or their families may have used and/or may feel defensive about to atrocities and 2) accusing his coworkers of supporting atrocities. That feels quite disruptive and inappropriate in the work environment IMO.

wk_end··on Noam Shazeer Joins OpenAI
IMO people just use the term to mean “pro-Israel” rather than in any reference to the original meaning ("supporter of the idea of a Jewish state"). Which could mean any combination of “pro-American financial support for Israel”, “moral support for Israel in their various military actions”, “opposed to the creation of a Palestinian state”, “a belief that Israel should continue to exist as a Jewish state”, and so on. It's more about the broad political alignment than the specific meaning of the word.
wk_end··on Hospitals and universities repurposing drugs at 90% lower cost
> This is interesting because the USA claims to pursue a maximum capitalistic society

No it doesn't. This is silly.

Drug prices in the US are high for non-generic drugs because patent law gives the patent holder an artificial government-granted monopoly, which is blatantly not "pure" or "maximum capitalistic".

Generic drugs - where the free market does apply - in the US are as cheap or cheaper than in other countries. See [0]:

  U.S. prices for brand-name originator drugs were 422 percent of prices in
  comparison countries, while U.S. unbranded generics, which we found account for 90
  percent of U.S. prescription volume, were on average cheaper at 67 percent of
  prices in comparison countries, where on average only 41 percent of prescription
  volume is for unbranded generics.
[0] https://pmc.ncbi.nlm.nih.gov/articles/PMC11147645/
wk_end··on Game Engine White Papers: Commander Keen
I thought "I'm sure it's not intentional" would make it clear that I'm not assuming bad faith - actually the opposite, I'm assuming good faith.
wk_end··on Copper transport drug restores memory and clears toxic Alzheimer's proteins
I'm also not exactly on expert on this myself, take it with a grain of salt, but my understanding is that we don't really know what Alzheimer's is. To our knowledge there isn't a clear physical cause we can point to - a virus or bacteria or tumor or something. We have the symptoms, and we have the observation that Alzheimer's patients have amyloid plaques in their brain - among other differences!

Since mice don't ever get Alzheimer's naturally, and we don't actually know what Alzheimer's is, we don't know what it would even mean to give mice Alzheimer's. But for research we've genetically engineered mice that end up with lots of those plaques, and their behaviour does suggest an impairment similar to Alzheimer's, so that's what we've been working with. And in those models, various treatments that involve clearing the plaques does seem to help resolve that impairment - but they don't help humans with Alzheimer's, even if they do clear the plaques there too.

If I'm reading your question correctly, we can't stimulate amyloid plaque growth in humans for experimentation because that'd almost certainly be considered completely unethical. And also our methods for inducing the amyloid plaques involve mice that are genetically modified from birth rather than something we introduce in vivo, which would somehow be even more unethical than experimenting on live humans. It's possible we could make those genetic modifications in vivo now with recent developments in gene therapy, but...why?

wk_end··on Game Engine White Papers Commander Keen
I get what you're saying, but the comparison to "racing the beam" is maybe a little misleading, because the point is that you aren't "racing" the beam. Rather, the system is operating in perfect lockstep with the beam. From the software perspective, you set the scene up and then sit back while it draws. And then in the abstract and from the hardware's perspective it's not even one line at a time, it's one dot at a time.
wk_end··on Game Engine White Papers Commander Keen
Yeesh, until I saw your comment I thought this was Fabien. I'm sure it's not intentional but this goes beyond "homage" and into "deceptive". The replies to this claiming to not see what the issue is are inexplicable to me.

The work on the book itself looks fantastic, so it's a shame about the site design.

wk_end··on Copper transport drug restores memory and clears toxic Alzheimer's proteins
In general, sure, but in this specific instance (treating Alzheimer's by clearing amyloid-beta) it's been shown over and over again to not work in humans.
wk_end··on What happened to nerds?
That's because it was illegal for lawyers to advertise their services until 1976. See Bates v. State Bar of Arizona:

https://en.wikipedia.org/wiki/Bates_v._State_Bar_of_Arizona

wk_end··on Not everyone is using AI for everything
I absolutely do want to work with people who want to think jointly about interesting questions for a couple of minutes. Give me your long-winded (thoughtful!) answers. Let me see how you think. Let me see how well I (and others) can think through things with you. That's what the point of an interview is, IMO. And I've been gainfully employed in tech for 15 years now with that attitude, often in environments with other like-minded folks, often involved in the hiring decisions that have led me to work with those other like-minded folks.

So in the same interest of helping post-grad job seekers, do what you've gotta do to get yourself paid, but maybe don't presume that vibe_that_works speaks for every hiring manager.

wk_end··on Orthodox C++ (2016)
How important is that, the ability to be certain of the type of some iterated value from a container from one line in total isolation? The odds are very good that it's clear from the context, which is why the compiler can infer it easily enough too. And then the consequence of not inferring correctly would be...the code doesn't compile?

Of course some discipline is required - as with just about everything in programming, especially in C++ - but developers in just about every other statically-typed language lean on type inference (including far more extensive type inference) and don't wring their hands about it. It's hard not to see this as a case of Blub - if you learned about typing with `Foo foo = new Foo()`, anything different might seem scary.

...anyway, in this case the real win probably is the range-based for loop, rather than the auto. `for (const Foo& foo : foos)` isn't so bad, but `for (std::vector<Foo>::const_iterator it = foos.begin(); it != foos.end(); ++it)` is pretty rough.

wk_end··on Vinyl succumbs to Loudness War: more than just collateral damage (2025)
That's just not true. I just had my band's album mastered; we weren't in the room or anything but the mastering engineer asked us directly questions about how we wanted the record to sound and we got final approval on it.
wk_end··on Vinyl succumbs to Loudness War: more than just collateral damage (2025)
I dunno if you’ve listened to these records in question but it’s very, very obviously for artistic effect. They’ve discussed it in interviews and stuff. Low wasn’t looking to get radio play with fractured collages of distorted noise. The “vinyl can’t reliably reproduce these waveforms” explanation someone else suggested makes the most sense.
wk_end··on Vinyl succumbs to Loudness War: more than just collateral damage (2025)
The loudness and compression on Low's last couple of albums is very much deliberate, so it's surprising that the vinyl doesn't have it. Though I heard similar claims about Sleater-Kinney's The Woods, which was also intensely compressed for artistic effect.
wk_end··on World Capitals Voronoi
BC's intact too, if I'm reading this correctly. We lose some far north to Iceland and the very southern tip of Ontario to the US, and that seems to be it as far as I can tell. And as a trade we get New England, a good chunk of Washington, and the northern Plains and a bit of the Midwest. Not bad, really!
wk_end··on Smudging the game disc to make speedrunning 'SpongeBob' faster
There's a belief in certain corners of the gaming community (and maybe other communities that deal with optical discs) that if the disc drive's laser has to "try hard" to read a disc it will eventually "burn out". Not sure if this is backed up by any actual data or facts - it sounds plausible to me that a laser might dynamically adjust its power level as needed, and that over time that might be bad for it; but it also sounds a bit like people might be anthropomorphizing the laser or something.
wk_end··on Stop the Apple Music app from launching
If there’s no media session available, “play” isn’t an action that makes any sense, so it shouldn’t do anything IMO.
wk_end··on Linux/M68k
Well, this page/project certainly isn't, but Wikipedia says it's still in the kernel:

https://en.wikipedia.org/wiki/List_of_Linux-supported_comput...

wk_end··on Linux/M68k
But it makes a kind of sense, right? There's long been straightforward upgrade paths for 486 users, making the 486 effectively totally obsolete and killing most of the demand for continued support. Whereas 68k machines have effectively become trapped in time, and their users are still going to work to keep support going.
wk_end··on Let's compile Quake like it's 1997
I could've sworn VC++6 had Intellisense. I'm not going to dig too far to confirm but Wikipedia seems to agree with me (https://en.wikipedia.org/wiki/Code_completion#Visual_Studio) - it's not a great reference but definitely implies that it was there:

> the Visual Basic versions of IntelliSense were always more robust and complete than the 5.0 and 6.0 (97 and 98 in the Visual Studio naming sequence) versions of Visual C++

wk_end··on Neutron scattering explains why gluten-free pasta falls apart (2025)
Indeed, blessed by His noodly appendage.
wk_end··on Why Japanese companies do so many different things
Not really? If I were to describe the issues inflicting the west, none of too-small homes, high suicide rates, or an economy based on long hours of white collar work would immediately come to mind.

Rather, the west seems to be characterized mostly by insanely expensive housing caused by an extreme antipathy towards denser housing as populations grow, and a K-shaped economy where white collar coastal elites are actually doing relatively well but everyone else - namely blue collar and service workers - are doing worse and worse. Suicide rates aren't rising dramatically, and are nowhere near where they were in Japan at their peak in the 80s, which itself was always overstated (they were higher than they were in the US at the time, but were comparable to many other western countries).

wk_end··on Why Japanese companies do so many different things
I really don't really think there's much political or propaganda interest in getting Westerners to idealize Japan, at this point.

Now back in the 80s? Back in the 80s, despite being aligned with the West, they were perceived a lot like China is today. Everyone was scared that they were going to start eating the West's lunch and various negative stereotypes and exaggerations started to bubble up: it was a futuristic land, but a futuristic land of suicides, with little drone-like salarymen crammed into little shoebox apartments the size of a Western bathroom, working 20 hour days.

Between the Plaza Accords and the bubble bursting and decade after decade of Lost Decades, the Japanese threat was successfully neutralized. I think Cool Japan is mostly something they've earned for themselves, frankly.

wk_end··on Alberta to hold referendum on whether to remain in Canada
> This seems extremely surprising - I've never heard of this sort of thing before with any other country.

It's a little surprising - even as a Canadian - if you're unfamiliar with Canadian politics/history/civics, but Canada is more loosely held together than most other countries, including the US. And a comparison with the US is instructive, because Canada's founders were unifying the country the wake of the US Civil War and were working very much in response to it: there was a fear that the US would turn imperial in an exercise of national unity and begin trying to snatch up the rest of the continent from the British and a belief that the British wouldn't care to defend them, which was arguably the primary motivation for Confederation: to form a unified front against American expansionism. And the Fathers of Confederation had seen how horrible the Civil War was and wanted to prevent that sort of thing from occurring, so the provinces - like in the US, formerly independent colonies - were given more power than the States, with the separation of powers clearly and rigidly defined.

The Clarity Act itself wasn't part of Confederation, but that's the cultural legacy that informs it: a civilized process allowing provinces to separate without bloodshed is just about as fundamentally Canadian as anything.

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