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trendia

3,191 karma · joined September 1, 2016

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trendia··on Texas Instruments CEO Brian Crutcher resigns for violating code of conduct
Sounds like NumWorks [0]

[0] https://www.numworks.com/

trendia··on Link Between Alzheimer’s and Herpes
"Acyclovir crosses the blood-brain barrier, a desirable quality for the treatment of herpes encephalitis, neonatal herpes simplex virus infections, and, possibly, multiple sclerosis" [0]

"The bioavailability of orally administered acyclovir is limited to 15 to 30% (23), and the level of passage across the blood-brain barrier has been assumed to be low, probably due to the relatively low lipophilicity of acyclovir (8). It was previously found (14) that upon oral administration the acyclovir concentration in cerebrospinal fluid (CSF) is only 13 to 52% of that found in plasma. When sustained and high concentrations of acyclovir in plasma are desirable, improved bioavailability can be achieved with valacyclovir, the hydrochloride salt of the l-valyl ester of acyclovir." [1]

[0] http://aac.asm.org/content/54/3/1146.full

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC166099/

trendia··on Sky-High Deductibles Broke the U.S. Health Insurance System
We still don't have price transparency, so it's not surprising the customers of health don't shop around.

I went to a grocery store health clinic without insurance and asked how much it would cost to see the doctor.

They were surprised I asked how much it cost, since they just assumed my insurance would pay for it. After insisting, I finally was able to get them to look it up. They told me it would be $100, but during my exit (and payment) they increased the price to around $200 based on my diagnosis. I asked why it should cost me more money for the doctor to diagnose me with something else, when the doctor didn't do any other special tests (e.g. I wasn't paying for a medical test), and they said "That's just the way it works."

trendia··on China Begins Production Of x86 Processors Based On AMD's IP
Did the Senate ask the CIA to spy on them?

"An internal investigation by the C.I.A. has found that its officers penetrated a computer network used by the Senate Intelligence Committee in preparing its damning report on the C.I.A.’s detention and interrogation program. "

https://mobile.nytimes.com/2014/08/01/world/senate-intellige...

trendia··on Is the Alzheimer's “Amyloid Hypothesis” Wrong? (2017)
In the context of the infectious disease hypothesis, do you know why caffeine / coffee would be associated with lower incidence of Alzheimer's? (It reduces amyloid-beta levels, but if plaques are not the cause of Alzheimer's then this shouldn't provide any protective benefit)
trendia··on Is the Alzheimer's “Amyloid Hypothesis” Wrong? (2017)
The amyloid, T3D, and viral hypotheses still don't explain why cholesterol, obesity, air pollution, lack of sleep, and sedentary liftestyle positively correlate with Alzheimer's and high caffeine intake and regular exercise negatively correlate with it.
trendia··on Google Downranks 65,000 Pirate Sites in Search Results
Source?

Wouldn't these people need to be specifically from the search team, and not Google in general (which would have almost no control over search)

trendia··on Filezilla installer is suspicious again
When I use apt-get I am downloading from debian.org, where at least there will be a record of what was executed. Further, I trust debian.org more than some random github repo.

When I use curl|sh, I could execute hidden text, e.g. through a Javascript command, which automatically executes the code and then deletes it from my history. At a future date, there is no way for me to know whether something malicious was executed, since the website may remove the malicious code when they get called out.

trendia··on On the Rise of FinTechs – Credit Scoring Using Digital Footprints
I love that "Do not track" is not interpreted as an instruction to not track but rather as an additional 1 bit of discriminatory data.
trendia··on Researchers Find Herpes Viruses in Brains Marked by Alzheimer's Disease
Acyclovir improves outcomes in HSV encephalitis [0], but does not completely cure it or prevent long-term damage in all patients.

The worst side effect of encephalitis is memory impairment:

> The most common and most disabling complication of herpes simplex encephalitis in our patients, and in other studies,9 10 20-24 was memory impairment, which especially affected short term memory. Occasionally remote memory is more severely affected than anterograde memory.

[0] https://jnnp.bmj.com/content/63/3/321

trendia··on How Firefox is using Pocket to try to build a better news feed than Facebook
> Firefox is about letting you control your browser experience

The true history of Pocket suggests otherwise -- in 2015 Mozilla integrated Pocket, which was at that time a private company separate from Mozilla, into Firefox.

Further, when Mozilla first integrated it into Firefox, there was no way to remove it, only hide the icon:

> "This page http://help.getpocket.com/customer/portal/articles/1999137-h.... purports to tell you how to disable Pocket for Firefox, yet all it does is remove the button from the toolbar. Searching "pocket" in about:config reveals numerous preferences that can be edited, including browser.pocket.enabled which remains set to true after following Pocket's instructions."

Only after severe backlash [0] did Mozilla decide the best way to handle it was to purchase Pocket.

[0] https://news.ycombinator.com/item?id=9667809

trendia··on How Firefox is using Pocket to try to build a better news feed than Facebook
I moved to the ESR branch specifically to get a web browser that just browses the web. (It's the default in Debian for that very reason!)

However, version 60 added pocket, along with other "features" such as the optional Firefox experiments (where, if you opt in, they track your user behavior to improve the browser).

Guess I'll be looking for a new browser again.

trendia··on Married in Montana: Servicemembers take advantage of state’s double-proxy law
> the giver can sue the receiver to recover the ring if the engagement is broken off.

Which contradicts the whole idea of an engagement ring:

> In the United States, until the Great Depression, a man who broke off a marriage engagement could be sued for breach of promise. Monetary damages included actual expenses incurred in preparing for the wedding, plus damages for emotional distress and loss of other marriage prospects. Damages were greatly increased if the woman had engaged in sexual intercourse with her fiancé.[32] Beginning in 1935, these laws were repealed or limited. However, the social and financial cost of a broken engagement was no less: marriage was the only financially sound option for most women, and if she was no longer a virgin, her prospects for a suitable future marriage were greatly decreased. The diamond engagement ring thus became a source of financial security for the woman.

https://en.wikipedia.org/wiki/Engagement_ring#Purchase

trendia··on Bitcoin’s Price Was Artificially Inflated Last Year, Researchers Say
This may be true, but the government also has the power to control inflation, which limits the purchasing power of those dollars.

See: Venezuela, Zimbabwe, Germany ~1920

trendia··on Meme specialist job opening (one of those jobs that “didn't exist yet”)
Of course, the people who really had experience in Bitcoin in 2011 are not out looking for jobs...
trendia··on If the Robots Come for Our Jobs, What Should the Government Do?
My post is describing why minimum income would not result in everyone getting $50,000 a year.
trendia··on If the Robots Come for Our Jobs, What Should the Government Do?
To get everyone up to the poverty line and not have to cut government projects, you'd have to triple tax revenue.

Since the average tax burden for those making $500k+ is around 30% already, that would effectively mean taxing them at 90%.

I don't think it's politically feasible.

trendia··on If the Robots Come for Our Jobs, What Should the Government Do?
The total US tax revenue in 2017 was $3.422 trillion.

If you split that evenly among 300 million people, each would get $11,000, which is half of the poverty line of $22,000.

Even if you thought that little money was acceptable, to afford it you'd have to cut:

1. all military programs

2. all existing social security programs

3. all government infrastructure projects

4. all education programs

5. ...

trendia··on The Repeal of Net Neutrality Is Official
Utility companies usually enjoy both natural and state-granted monopolies for many reasons. The state grants them monopolies because cities don't want multiple companies laying conduits or having disputes over access to existing conduits. Imagine the difficulty of having 10 different cable companies, each wanting to lay cable throughout the city!

Even without state intervention, utility companies tend to become local monopolies, duopolies, or non-competitive oligopolies because of the high barriers to entry. This makes it difficult for startups to compete with the incumbents.

In this case, legislation is much more effective at handling the second-tier consequences of utility companies (e.g. the natural tendency away from competition) than handling the problem itself (the high barriers to entry)

trendia··on I’m Nat Friedman, Future CEO of GitHub. AMA
Facebook's earnings are driven by their ad network, not user interaction.

That is, as long as Facebook is able to identify and track an individual, they can make money even if the user never spends much time on Facebook.

So, stock price is not an indicator of Facebook usage.

trendia··on Caffeine dosing strategies to optimize alertness during sleep loss
Genetics play an important factor. CYP1A2, one of the enzymes that metabolizes caffeine, varies by as much as 40x between individuals.

In those with a high level of the enzyme, caffeine is metabolized quickly, so they can drink coffee in the afternoon and still fall asleep. They are less likely to get anxiety from caffeine, and do not suffer from a higher risk of heart attacks with coffee consumption.

In contrast, a small amount of CYPA12 prevents caffeine from being metabolized and prolongs its effects.

[0] https://en.wikipedia.org/wiki/CYP1A2

trendia··on Behind the Messy, Expensive Split Between Facebook and WhatsApp’s Founders
The source of Facebook's revenue is its ad network, not the use of its social networking capabilities at facebook.com

If you visit a news site and click on an ad that was shown through Facebook's ad network, then they receive money. Importantly, you don't need to use facebook.com that much, only enough for Facebook to start tracking you.

If a Facebook user logs into their account just once, then the Facebook tracking cookie will log their visits to other sites in the ad network, which is the second largest network next to Google's. If they click on an ad, then Facebook receives revenue -- it isn't necessary for the user to be using Facebook in order for Facebook to receive money.

trendia··on GitLab Ultimate and Gold now free for education and open source
I understand the value of guerrilla marketing, but at the same time it makes them seem less credible.

Imagine if they offered a 75% discount for defending them or praising them on Hacker News! That would make any comment in support of GitLab suspect.

trendia··on Path ways to become a Future Physicist
> why apple always fall towards the earth but not earth towards an apple?

But it does.

trendia··on Microsoft’s commitment to GDPR, privacy and customers’ control of their own data
I'm not convinced.

I run a Pi-Hole [0] to redirect all advertising-related queries to a black hole. When tracking the most-blocked domains, Microsoft is at the very top [1].

For instance, when I enter "Office" into the start menu, Microsoft immediately sends a ping to bing.com and Microsoft's telemetry servers. That is, Microsoft is sending all of the data entered into the start menu to Microsoft's servers, even when using the 'Pro' version and with 'full' telemtry off.

When it was first detected that Microsoft was adding telemetry calls to all compiled programs in Windows [2], Microsoft said it was mostly for event debugging for programmers. Now I'm not so sure -- look at your Microsoft account privacy settings to see that Microsoft tracks when you open applications. (They say on the page that not all data is shown there).

Unforutnately, there is no way to opt out of this. You can "disable" full telemetry, but you still have to opt into "Basic" telemetry, which still sends your advertiser ID, the programs you run, and the queries you put into the start menu. I'm concerned that Microsoft is not going to stop here. They have a real incentive to capture as much data about you as they can -- they currently earn about $1 billion in advertising through Bing.com search queries. Unlike Google or especially Facebook, however, it's much more difficult to opt out of Microsoft's tracking -- so many people depend on Microsoft Office or other Windows programs that I can't fully switch to Linux.

I don't know how this is acceptable through GDPR. There are so many problems with what Microsoft is doing:

1. There is no way to opt out of telemetry

2. There is no way to see all of the data that Microsoft has collected

3. Microsoft has severe lock-in because so much software is written for Windows-only

4. Microsoft has an incentive to increase their telemetry, not decrease it.

[0] https://pi-hole.net/

[1] https://imgur.com/a/MbjtYJe

[2] https://old.reddit.com/r/cpp/comments/4ibauu/visual_studio_a...

trendia··on Google sued for 'clandestine tracking' of UK iPhone users' browsing data
On a broader scale, the NSA had William Binney implement a way of vacumming up data, but the system include Constitutional protections and required a warrant to access.

Once it was implemented, the NSA took him off the project and put other people on to remove the controls.

trendia··on GDPR Hysteria Part II, Nuts and Bolts, Actionable Advice
I would like to know how this will affect Microsoft.

I run a Pi-Hole [0] to redirect all advertising-related queries to a black hole. When tracking the most-blocked domains, Microsoft is at the very top [1].

For instance, when I enter "Office" into the start menu, Microsoft immediately sends a ping to bing.com and Microsoft's telemetry servers. That is, Microsoft is sending all of the data entered into the start menu to Microsoft's servers, even when using the 'Pro' version and with 'full' telemtry off.

When it was first detected that Microsoft was adding telemetry calls to all compiled programs in Windows [2], Microsoft said it was mostly for event debugging for programmers. Now I'm not so sure -- look at your Microsoft account privacy settings to see that Microsoft tracks when you open applications. (They say on the page that not all data is shown there).

Unforutnately, there is no way to opt out of this. You can "disable" full telemetry, but you still have to opt into "Basic" telemetry, which still sends your advertiser ID, the programs you run, and the queries you put into the start menu. I'm concerned that Microsoft is not going to stop here. They have a real incentive to capture as much data about you as they can -- they currently earn about $1 billion in advertising through Bing.com search queries. Unlike Google or especially Facebook, however, it's much more difficult to opt out of Microsoft's tracking -- so many people depend on Microsoft Office or other Windows programs that I can't fully switch to Linux.

I don't know how this is acceptable through GDPR. There are so many problems with what Microsoft is doing:

1. There is no way to opt out of telemetry

2. There is no way to see all of the data that Microsoft has collected

3. Microsoft has severe lock-in because so much software is written for Windows-only

4. Microsoft has an incentive to increase their telemetry, not decrease it.

[0] https://pi-hole.net/

[1] https://imgur.com/a/MbjtYJe

[2] https://old.reddit.com/r/cpp/comments/4ibauu/visual_studio_a...

trendia··on Today’s dominant approach to A.I. has not worked out
Why have autonomous agents talk to each other? It is vastly simpler to fill out an online form.
trendia··on Devices Which Track Cellphones, Intercept Calls Found All Over DC, MD, VA
Honest question:

If an embassy started blaring very loud music (or a siren), can the US do anything about it?

Likewise, if they started emitting strong microwaves at people, can the US do anything about it?

It seems like there must be some limitation to what you can do from the embassy to people outside of it.

trendia··on Theranos Inc.’s Partners in Blood
> Timothy Draper, the well-known venture capitalist, had been a neighbor when the Holmeses lived in California. The children played together. “I gave her her first million bucks to get the business going,” Mr. Draper says. “She totally blows me away with her vision.” [0]

[0] https://www.nytimes.com/2015/12/20/business/theranos-founder...

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