The fact that OPs is "controversial" isn't actually set in any science, it's set in extra-scientific mushrooms-as-religion mentality that is currently proliferating as the "current thing".
A drug-based solution to depression, anxiety, etc would be incredible, but unfortunately outside of humanity's reach today.
If you're not interested in science and instead seeking religion, skip the drugs and reach for your closest religious text and start reading. As a Catholic I recommend the Gospel of Mark as a starting point. It's far easier to believe that multitudes of people 2000 years back witnessed some dope stuff and started following some rules that make everyone feel great today, rather than the universe transpired from nothing in some scientifically unprovable theory and potentially HPPD-causing substances are the only way to feel whole.