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ramraj07

10,847 karma · joined March 1, 2011

PhD in biomedical engineering, data scientist day before yesterday, software engineer yesterday, AI engineer + Director today. http://ramrajv.com

If you're emailing about the job post, mention this keyword in it: serenity

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ramraj07··on Amazon CEO's talks with U.S. officials triggered crackdown on Anthropic models
Im just curious how this is going to play out.. Will anthropic just stop releasing its stuff on bedrock now? Will they try to start moving their operations out of the US? If so, to where?

I know everyones excited about Football and the Knicks, but this is far more exciting and interesting than any sport could be.

ramraj07··on CRISPR tech selectively shreds cancer cells, including "undruggable" cancers
Devils advocate, I also vehemently shat on RNAi therapeutics a decade back. We do have RNAi therapies in market now though. I do think Crispr will find its place similarly.
ramraj07··on OpenAI mulls slashing prices as it competes with Anthropic for users
I regularly hit usage limits on CC but thats when im in the zone, and do 5 things in parallel. Thats like 5 hours a week.

I also hit limits if I do something important, at which point I make it do a loop with significant subagent counts to just review and adjust the code extensively using a bunch of frameworks. Im perfectly happy with the CC limits of a max plan, it is never something that blocks me.and when it runs out im brain fried as well anyway so thats not an issue.

ramraj07··on The Unreasonable Redundancy of Nature's Protein Folds
Competing with "x is all you need"
ramraj07··on Iron-rich immune cells help homing pigeons navigate
Such an elegant finding. I only wish they did slightly more to validate the result further. Depleting all macrophages is a fairly drastic step. Heck, you dont even know what other tissue this affected. Theres no correlation that only liver macrophages or their iron or neuronal connections were the responsible system for the disruption observed.
ramraj07··on ICE Awards $25M Iris-Scanning Contract to Bi2 Technologies
Thats not a bubble though, thats just Stockholm syndrome or genuine acceptance of this behavior as being acceptable or even perfect.
ramraj07··on Waymo pauses Atlanta service as its robotaxis keep driving into floods
They never advertised that they did. Its not even real true AI. They just struggle with new scenarios.

People drive into floods too. They just don't get sensational articles written about it, just posted on reddit.

ramraj07··on There's no earthly way of knowing which direction we are going
I really wouldn't care.
ramraj07··on There's no earthly way of knowing which direction we are going
What's wrong with the Polish author example?
ramraj07··on How Claude Code works in large codebases
You mean like Teslas multi terabyte repo is not normal?
ramraj07··on How Claude Code works in large codebases
The first step I do when I do any meaningful side project is to set up rds with snapshots. So any startup that doesnt do this one basic step already deserves to fail in my opinion.

Then next I've used AI agents like crazy, we even have linked mcp servers that let it query on the dev database. Haven't seen it try deleting everything a single time. I haven't seen any agent try to do anything destructive. Ever. Perhaps its just reflecting an outrageously bad engineer and nothing else.

ramraj07··on I'm going back to writing code by hand
The comparison is not valid. When writing let's say a novel, you cant just tell some random dude "write chapter 4" - you cant outsource it to a human so it only makes neither can you outsource it to ai.

Software engineering is not that. You absolutely can and often will hand ofoff work to humans. Its not inherently that creative in the actual coding part.

ramraj07··on Richard Dawkins and the Claude Delusion
I would argue unconscious in the anesthesia sense is not the same as "not having consciousness" at a categorical level.
ramraj07··on Richard Dawkins and the Claude Delusion
There is no true scientific discussion possible about the nature of consciousness. This is squarely in the realm of philosophy.

I personally think its moot to discuss whether LLMs are conscious. If they are, then we have diluted the definition to something that has no relevance to morality or concepts like life and death. Lets just take them for what they are, if we feel like they deserve to be treated with respect then we should (dont think anyone does yet).

ramraj07··on The agent harness belongs outside the sandbox
For 1, the general thinking is that companies like these perform the job of abstracting the CLI complexity in their application while the harness presented to the llm can be independently as suave as needed for it.
ramraj07··on The agent harness belongs outside the sandbox
No matter how smart you think you get, I personally dont trust the models in an environment where they can read the secrets one way or another, in any high volume production environment.
ramraj07··on The agent harness belongs outside the sandbox
> It assumes the existence of a sandbox that is by definition ephemeral or "cattle-like". Why?

Because the moment you use k8s, you have to assume that, apparently. Or so Im told by all the infrastructure people I speak with. Getting these pods to not disappear just because one process ran out of memory has been an herculean task.

I wish our standard deploy processes produce durable computers that dont break our bank but that hasn't been an easy requirement with simple infra teams.

ramraj07··on Claude system prompt bug wastes user money and bricks managed agents
Not even close to the same thing though.
ramraj07··on Pgbackrest is no longer being maintained
Backing up multi terabyte production postgres databases is not merely cos playing ha ha
ramraj07··on Why has there been so little progress on Alzheimer's disease?
What exactly do I need to say further? My first comment was that "scientists today still don't understand correlation =/= causation" and the replies are all scientists who try to explain again how correlation can still mean causation (no it doesn't, and it definitely doesn't in this case and that has been the root cause from the beginning). So I tried to implore you to go review your text yourself, but you are clearly above it, so not sure what else I could do here.
ramraj07··on Why has there been so little progress on Alzheimer's disease?
Wouldn't mind knowing how.
ramraj07··on Why has there been so little progress on Alzheimer's disease?
Im not gonna try to correct you because its probably going to be futile, but I implore you to paste this thread into chatgpt and ask where you could be wrong in your logic.

Correlation not causation is all the more important in a topic like this; nothing you said suggests amyloid causes alzheimers or just forms because of it.

ramraj07··on Why has there been so little progress on Alzheimer's disease?
> Autopsies of brains of Alzheimer's patients were rife with amyloid

Do you want think carefully about how this can possibly suggest this is a causal link?

> People with mutations that caused amyloid got Alzheimer's earlier than others.

People with mutations in those genes got a particular type of inherited alzheimers early, this says nothing about the cause of general Alzheimers.

ramraj07··on Why has there been so little progress on Alzheimer's disease?
There were no cointerarguments? There was a very simple counterargument: where was the causal data? If none exist why should I counter argue when you hadn't proven it to begin with.
ramraj07··on Oxford All Souls College General Examination (2025) [pdf]
https://www.asc.ox.ac.uk/people/245 perhaps you can take a look and decide?
ramraj07··on DuckDB 1.5.2 – SQL database that runs on laptop, server, in the browser
Did they finally enable full SIMD or keep insisting its okay not to have it?
ramraj07··on Multi-Agentic Software Development Is a Distributed Systems Problem
Curious idea (found your hn post) but cant figure out what the use case is..
ramraj07··on How Complex is my Code?
Its outrageous that no one pointed out git. Its the perfect example of this. I consider code version control a solved problem post git.
ramraj07··on I run multiple $10K MRR companies on a $20/month tech stack
Apparently the phrase cargo cult software engineering is not common anymore. Explains these things perfectly.
ramraj07··on How NASA built Artemis II’s fault-tolerant computer
Yep, spend 100 billion on what should have cost 1/50that cost, and send people up to the moon with rockets that we are still keeping our fingers crossed wont kill them tomorrow, and we have to congratulate them for dunking on some irrelevant career?
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