736 karma · joined May 10, 2018
>How would that look?
You really can't see the parallel? "There's data coming in that suggests the AZ vaccine is deadly to a small but significant population, so while we wait for more data, we're going to halt its use".
>Content of the statements does. Check them with your favorite evolutionary biologist or virologist.
The onus is on the person making the statements to back them up. What you've said on the subject sounds very reasonable, but I can't find anywhere else.
As for your linked article on the British variant B117:
"Dr. Julian Tang, honorary associate professor and clinical virologist at the University of Leicester, said in a statement that he is "still not yet very convinced by these results" from the study."
Because they can't yet control for winter conditions affecting health.
>I won't find you the data that doesn't exist yet.
Right, so not exactly something that you can base much on (yet). I could also make very similar arguments about the AZ vaccine, as a younger person.
Declaring your statements to be "basic evolution" does not make them true.
>How that milder variant is doing now? Compared to, let's say, the British one, or the Brazilian one?
The article was talking about the British one. I am also in the UK, and not dead. Yes, it was written soon after the initial outbreak, because Covid-19 mutated quite quickly. Using some similar fuzzy evidence, it would seem that "long Covid" sufferers are primarily people who caught Covid in March/April 2020.
>It's unclear exactly what the age breakdown is when it comes to this variant strain
It seems you need to spend more than 10 seconds researching your ideas.
The rest of what you've said in response to my requests for further information and sources is just personal opinion, presented as "reasonable" arguments.
>Becomming less deadly is a typical direction viruses evolve but at a time scale of hundreds and thousands of years, not few months.
An idea not supported by my 10 seconds of research:
https://www.newscientist.com/article/2252699-covid-19-is-bec...
>There were initially hopes that this virus won't be capable of evolving this fast.
I would ask for some sources to back that statement up too, but I don't hold much hope for a reasonable reply. Influenza is a non error-checking RNA virus, coronaviruses are error-checking RNA viruses. The slowest to mutate are DNA viruses. The relative speed of mutation of these types is well understood.
>You never heard that while viruses evolve they sometimes gain ability to spread to organisms they had trouble infecting before?
Yes, I have, but never in the context of "younger examples of the existing infected organism". Even so, and as I've already said, we don't even know if younger people are already being infected with the existing strains, so I can't get myself too worked up about hypothetical possible future variants.
You've also mixed in your personal opinions on supposedly how bad life was before Covid, how little you value small businesses, and how life should be drastically re-modelled so that everyone works and learns remotely. I disagree, but that's ok, it's opinion. I think that remote (learning or working) places people at a huge disadvantage - against those who already have in-person connections, and against institutions that have the sense not to do such a thing.
>sars-cov-2 is so mild in objective terms
We certainly agree here.
I'll need a soruce for that, as all reports I've read indicate that Covid has mutated the typical direction - that is, to be less deadly.
>Any novel virus evolves in ways that helps its spread into popularions previously unavailable for infection. And only after it is at risk of wiping populations it infects it evolves milder variants that are careful no to kill too many hosts to quick.
Also a source for that, as this is an idea I have never heard of before.
I haven't even seen any definitive answer whether younger people are just less affected by Covid, or really do not become infected. The whole "asymptomatic carrier" idea really makes it hard to prove anything.
Saying that, how will we stop a virus mutating with a vaccine that is between 60% and 90% effective at preventing symptoms, and with a currently unknown effect on transmission?
If we are just delaying the inevitable, then why wait? If it's about the young (which would be quite the reversal, as to date, it's all been about "not killing granny"), then we need to consider the effects of on-going lockdown and destruction of opportunity for young people (which is very real).
If I had been told at the start that we would be under effective house arrest until researchers had developed a series of vaccines with the intention of stopping Covid from mutating into hypothetical potentially worse variants, I would have called BS right then.
Edit: Also, interesting that you point out that "it became known that Covid mutates rapidly". That's not at all surprising, it's long been known that coronaviruses mutate fairly rapidly. In fact, whenever I pointed out this fact, and that it makes vaccine development difficult and pointless unless we are going for continual vaccination, the "online Covid expert" crowd gave me a lot of flak for it.
Using EVs to transition to something else, leaving behind craters and huge scars from mineral extraction, and huge amounts of e-waste, is just absurd on its face (but very profitable).
Exactly what about the mass extraction of lithium is at all sustainable to provide the energy storage for all motorised personal transport?
I have recently completed a digital purge, and now have no social media accounts at all (except HN), and no smartphone. Fortunately I live in a country where that is still viable, but I am excited to re-build my life in "real life".
Taken as a proportion of total Covid deaths, that is very true.
Given that practically no young people die in developed countries, it doesn't take much to make a big change to the excess mortality figure for that age group.
Also - Google is the natural result of the Silicon Valley business model. You got what you wanted!
Edit: It seems that not even Silicon Valley likes the monsters it has created.
As you (and the article) say, much more research is needed.
For those reasons, along with the lack of any information as to whether the vaccine has a meaningful effect on reducing transmission, I have decided that the risk (relative to the reward) to me is too high.