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mlerner

2,073 karma · joined April 24, 2008

Software Engineer and computer security explorer.
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mlerner··on Coinbase Index Fund
The Bitwise HOLD10 (run by Bitwise, where I work) rebalances every month.
mlerner··on Coinbase Index Fund
I work at Bitwise Investments (venture backed by Avichal Garg - a YC partner), and some people know us as "the first cryptocurrency index". We think Coinbase releasing an index is great for the space - diversification is super important for a crypto portfolio and it is good to see other people working on the problem. We offer a different basket (Coinbase only offers the coins available on Coinbase), have different business model incentives, and different focuses.

If investing in a diversifed portfolio seems intriguing to you, and Coinbase's offering doesn't fit your needs, you should check us out: bitwiseinvestments.com

Also, we're hiring!

mlerner··on Next Big Thing, a HN-like site for music content
This seems similar to The Hype Machine. A site that gauges taste in music really needs lots of people using it for the "popularity" of a song to be useful.
mlerner··on Synthetic biology is heading for the cloud
Intern from Teselagen here. <shameless plug> We have a private Beta that you can sign up for on our website if editing your own DNA sequences is appealing to you: http://www.teselagen.com/user/registration </shameless plug>

It's pretty cool to see Synthetic Biology getting coverage on HN. One of the really interesting ideas that scientists are starting to grab a hold of is that of "biological parts". People have started compiling these biological circuit elements and figuring out how they work when exposed to different stimuli [1]. The ultimate aim is to standardize the usage of these parts so that you could design an organism in your browser, figure out whether it will work or not (based on a super-secret algorithm), and get the resulting functional organism shipped to your lab bench in a couple of days. As a reference, right now it can take up to 2 months to even create an initial DNA product with traditional methods. From there, it could take months to get your organism working correctly. New DNA synthesis techniques will dramatically speed up some of the initial steps (something Teselagen has done).

An addition to the article I'd make is that Teselagen is actually letting people leverage new DNA synthesis techniques produced by a couple of groups (the Venter institute is one) to design better biological circuits (as in faster, better, stronger). If you are interested in reading about how scientists have begun to overcome some of the many barriers to biological circuit design, there's a good intro to advances in DNA synthesis techniques here: http://j5.jbei.org/j5manual/pages/1.html

[1] partsregistry.org

mlerner··on Show HN: A better way to track fitness goals (my nights and weekend project)
Is this very different from what Strava [1] is doing?

[1] www.strava.com

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