mapme

I think that’s a large oversimplification of Facebook. While it’s true a lot of FB storage is MySQL backed they also created many complex systems such as:

- Cassandra (based on dynamo/big table)

- wrote a custom KV store named RocksDb that is open source/now a company

- wrote a custom photos storage system that replaced an NFS based design

- wrote another custom binary object store

- wrote a custom geo distributed graph db (Tao)

- wrote an in house distributed FS replacement for HDFS

https://www.cs.cornell.edu/projects/ladis2009/papers/lakshma...

https://www.usenix.org/legacy/event/osdi10/tech/full_papers/...

https://www.usenix.org/system/files/conference/osdi14/osdi14...

https://www.usenix.org/system/files/conference/atc13/atc13-b...

https://www.cs.princeton.edu/~wlloyd/papers/tectonic-fast21....

https://m.facebook.com/nt/screen/?params=%7B%22note_id%22%3A...

4.5 billion in ads per year on 200 mil users is a failure? What revenue number would you define as successful?

That is an interesting comparison to other reasons why we kill animals, however, the point wasn’t a relative moral comparison to animal slaughter for food purposes but that it’s not zero cost morality wise to kill an animal in its prime.

I understand your view and agree with what you’ve said, however, the primary point was that there are moral implications if you intervene in another life so it is not a moral freebie.

Wouldn’t you need to kill the animal in the prime of its life, causing a moral issue?

Actually in Japan you could argue drinking was somewhat required for their livelihood lol it’s different than driving requirements but interesting nonetheless

https://www.google.com/amp/s/ameliemarieintokyo.com/en/nommu...

Better to go with N100 mask or heavy duty respirator if you truly wanted to ramp up protection. https://www.grainger.com/product/6AD97?ef_id=Cj0KCQiAw9qOBhC...

It’s wild that manhattans population was ~2.5 million in 1910 and is now only ~1.6 million.

Exactly, the attack rate of vaccinated individuals who are infected is significantly lower.

Did you read the linked article? The governor of one of the largest US states asked hospitals to delay elective procedures to ensure hospital capacity.

For me the major point of vaccinating others is ensuring hospitals are not overwhelmed and have enough capacity to treat other patients and perform elective procedures.

https://www.google.com/amp/s/www.politico.com/amp/news/2021/...

I think you misunderstood the quote. It is saying that if you take 10 million people the background rate of death, disease, stroke etc., (unrelated to vaccine) will be high and a confounding issue, even if you didn’t give them the vaccine.

Edit: I think you have a point about whether those who have previous infection truly need the vaccine, but the way you are using VAERS data diminishes your point

You have to compare it to the background rate to tease out signal from noise. That said any intervention (including a vaccine) carries non-zero risk. Taking aspirin, Zantac, laxatives, NyQuil etc., all can destroy you, but it’s rare.

The safety monitoring is actually pretty good as well. We caught a 1 in ~100k issue with AZ/JnJ vaccine very early on in the rollout. We caught mild myocarditis (though COVID risk > vaccine for myocarditis). There was even a massive preprint today from Israel around vaccine side effects. Few were concerning. Link to study + summary https://twitter.com/erictopol/status/1430636357626466307?s=2...

> “ Bob Wachter of UCSF had a very good thread on Twitter about vaccine rollouts the other day, and one of the good points he made was this one. We’re talking about treating very, very large populations, which means that you’re going to see the usual run of mortality and morbidity that you see across large samples. Specifically, if you take 10 million people and just wave your hand back and forth over their upper arms, in the next two months you would expect to see about 4,000 heart attacks. About 4,000 strokes. Over 9,000 new diagnoses of cancer. And about 14,000 of that ten million will die, out of usual all-causes mortality. No one would notice. That’s how many people die and get sick anyway”

The policy excludes children under 12 given they are not eligible.

It is much more effective than the flu vaccine and you can still transmit with the flu vaccine, as neither are purely sterilizing.

Currently it’s actually the opposite in that the best restaurants are thriving because they ~doubled capacity by adding huge outdoor dining structures on the sidewalks that were previously not allowed. Note that it only impacts indoor dining not outdoor and that some restaurants, gyms, and venues has already begun to require of their own volition.

I find it hard to believe they “didn’t want the public to know” when one of the earliest studies the CDC did on vaccines, with a March 2021 publish date, was a study that tested weekly regardless of symptoms to see if it prevented infection outright. Maybe not perfect sterilizing immunity but it does prevent asymptomatic.

I agree they didn’t get into the nuances of sterilizing vs. non sterilizing but for the general public that’s deep in the weeds, anyone who followed the details knew this was the case early on.

> “One of this study’s strengths is its design: participants self-collected nasal swabs each week for RT-PCR laboratory testing, regardless of whether they had developed symptoms of illness. Researchers were able to look for evidence of SARS-CoV-2 infection irrespective of symptoms. A small number (10.7 percent) of infections in this study were asymptomatic (i.e., did not result in symptoms). However, the majority of infections (58 percent) occurred among people whose infections were identified by testing before they developed symptoms or knew they were infected. The study demonstrates that these two mRNA vaccines can reduce the risk of all SARS-CoV-2 infections, not just symptomatic infections.

This is important because preventing both asymptomatic and pre-symptomatic infections among health care workers and other essential workers through vaccination can help prevent the spread of SARS-CoV-2 to those they care for or serve. Findings from this study complement earlier reports that these two mRNA COVID-19 vaccines can reduce both asymptomatic and symptomatic SARS-CoV-2 infections.“

https://www.cdc.gov/media/releases/2021/p0329-COVID-19-Vacci...

Genuine question: were people ever reading the source material? Seems like a dubious claim that folks of yesteryear read deeply into original sources. Most people read headlines and attention grabbing quotes and this was just as true 100 years ago. I recently read about the Russian revolution and it was similar to today.

I think that’s because the American urban centric view looks at where the meat comes from in the US and it’s not equivalent to hunting on a farm. It comes from factory farms that are pretty sickening when you see videos and pictures. Sure maybe some folks in rural areas or hunters are similar to what you described but 95% is factory farms in US supermarkets.

Also part of the point is that in this culture it’s not for survival. If you need it to survive that’s a different story and not what most people dislike. However US consumers have a choice, so why not make the best of it. Choose meat from sustainable farms or just avoid it.

A notable exemption:

“The bill includes a clause that exempts a company "that owns and operates a theme park or entertainment complex" - which allows Disney to be exempt from this bill. Florida is home to the Disney World theme park.”

The easiest path is to read Designing Data Intensive Applications by Martin Kleppman. Builds from the ground up and by the end (or after a second read) you will have a deep understanding. Book hits on all of of the tech you mentioned except Kube. For that read one of the original google papers on cluster management systems eg. Omega

I wish the US had gone harder on telling people to get quality masks. Personally I use only n95 from US manufacturers that have a tight seal around my face. I understand before that there were supply constraints, but also there are better fabrics than just cotton that are widely available such as chiffon, which block/filter a ton more than cotton and is widely available.

Isn’t that direct evidence that medical masks work? Which doesn’t support your assertion that groups all masks together. Thus, your argument appears against cloth masks, not medical grade (surgical, n95).

https://bmjopen.bmj.com/content/bmjopen/5/4/e006577/F2.large...

I wouldn’t say nefarious but just extremely delayed which leads to bad outcomes. This was known for at least the last 6 months and it then let places hide behind this as being safe (we follow cdc guidelines!). Restaurants saying they clean the tables vs. having a hepa air purifier.. buses cleaning seats vs. mandating windows be open etc. etc.

How does rate of community spread impact efficacy calculations? The placebo and treatment group should be operating in similar areas w/ similar case rates. If there were 10,000 cases in placebo and 1,000 in vaccine, how is that different from 1,000 in placebo vs 100 in vaccine? Not read out to the same efficacy.

Israel has much more robust data than the trials for pfizer (monster study group size of 600k per group). They have seen hospitalizations and death in fully immunized individuals. There’s more papers out there but here’s one.

https://www.nejm.org/doi/full/10.1056/NEJMoa2101765

A mild reaction to the vaccine is way different than actually having a viral infection. Potential long term persistent symptoms can occur with viral diseases and particularly COVID. Not sure that comparison makes sense.

Additionally JNJ has side effects as well.

The positive note is that we are already at 74% of over 65 w/ one dose, so hopefully we can push that to 85% and drastically lower deaths. Vaccine acceptance in 65+ is very high

Yes, this was seen in the Israel Pfizer data that death protection was around 93%. There are a number of public data points from Israel with sample sizes that dwarf anything done in trials. Shame it’s not mentioned more as it’s incredibly robust (positive) evidence

CDC study from this week showed 90% effectiveness when doing proactive weekly testing regardless of if presenting symptoms. That is the best data I’ve seen as evidence it prevents even a symptomatic cases as a very high efficacy. Israel data claimed it was highly effective on a symptomatic but their methodology was off (for how they defined a symptomatic)

https://www.cdc.gov/mmwr/volumes/70/wr/mm7013e3.htm?s_cid=mm...