jnathsf

“Interestingly, we identified three major pathways that help explain the links between red and processed meat and cardiovascular disease—microbiome-related metabolites like TMAO, blood glucose levels, and general inflammation—and each of these appeared more important than pathways related to blood cholesterol or blood pressure,”

And LSD

I just sat and counted my breathing. If things got hard I would listen to some guided meditation.

I agree - we spend so much time communicating via a keyboard and yet few of us take the time to learn how to touch type. Was there any specific website/app that helped you improve your typing - I know there's a ton of free resources out there.

Did you also see valuable engagement with your writing that led you to generate new ideas? Also would be interested in any links you can share.

how was the writing important part of your success? Did it create new connections and opportunities that you wouldn't have had otherwise?

How is your product differentiated from the many other SaaS players and OSS libraries that have similar (and often more) features?

This is exactly the approach SF[1] was taking but unfortunately our main political champion, the Mayor, passed away unexpectedly. We were estimating $25-30/mo for 1Gb symmetrical as a utility tax for all households (subsidized for low income).

[1] https://www.washingtonpost.com/technology/2018/07/12/america...

We're hiring Ruby engineers. Check my bio to drop me a note.

We looked at Linear and decided on Kitemaker[0] as their core thesis is enabling collaboration with eng and product (and other stakeholders). The team does daily deployments and like Linear they focus on speed and hotkeys.

[0] https://kitemaker.co

Like many startups we've struggled with velocity vs quality doing the standard unit test for each PR and full regression tests for bigger changes. But it's never really worked well.

Ran into a blog post by Rainforest's CEO [1] that really resonated with me on why the status quo in testing is broken (it's all about misalignment of incentives).

My team did a bake off and Rainforest was the clear winner. What Rainforest has built is a big technical achievement and they make it look so easy! We're just getting started with them but we have high hopes that we can better balance velocity and quality.

[1]https://www.rainforestqa.com/blog/accessible-quality

About 50% of SF has above ground wiring and Sonic offers 1gig symmetrical in those neighborhoods at a reasonable cost.

For me the catalyst for change was a period of personal transformation fueled by psychedelics. Another “addiction” I gave up during this time was meat. It’s been 20 years and I’ve been fortunate not to have any desire for either.

I want to acknowledge how incredibly difficult it can be to give up smoking and express my support to all of you who are trying. I hope you find your path.

Is the code open source?

This is amazing! I’d love to chat about what we’re doing with streamlining govt procurement and how your gem could be very useful.

We solved for this by giving Amazon gift cards - I believe you can have them go up to $2K

>MSP-1014 has the potential to be a safer, more efficacious analog to psilocybin, with reduced potential side effects

Isn't psilocybin already extremely safe? This seems to be more about capitalizing on psychedelics by tweaking a natural substance to make it patentable.

What would be interesting is the psychedelic equivalent of Narcan.

Many have gone California sober [0] - moving away from alcohol to cannabis and psychedlics as a way to be more healthy and sustainable

[0] https://www.addictionresource.net/blog/california-sober/

What’s Microsoft’s news?

Deloitte is using salesforce for the underlying technology of the system. So almost all of this work is configuration and maybe some customization. We worked with another state that almost selected Deloitte but they bombed the no cost bake off and ultimately chose another vendor which completed 80% of the work during the bake off. This approach lowers risk dramatically and you’re able to set an aggressive and a more accurate launch date.

I hope we see more govts adopting bake-offs for buying IT.

I'm not sure the author read Ram Dass' book or knows of his life as the author mentions Buddhism several times but clearly Ram Dass is a Hindu (his name means servant of Ram, a Hindu god, and his guru was Hindu).

Key take aways:

* If your community has few essential workers, stay at home white collar workers will keep your infection rate down (see East Palo Alto vs SF)

* Having world-class public health universities is a big advantage (Stanford vs UCSF)

* Control outbreaks in vulnerable locations like Skilled Nursing Facilities

* Having an educated mask wearing public is helpful but not a big driver

That’s the cynical perspective.

The flip side is that the US has traditionally attracted the best talent in the world. This class has gone on to win the most Nobel prizes and create the most valuable companies in the world. Focusing on a real negative externality (labor arbitrage) fails to recognize the immense benefits skilled immigrants bring to this country.

I’m a son if one of them. My dad came this country in the 60s to get his masters in math at BYU. Probably the only South Asian in the entire class. He overcame extreme poverty,(half of his siblings died in childhood), disabilities to go on and achieve so much. I benefit from his achievements and being a US citizen.

That being said, we’re losing our preeminence due to growing xenophobia and a strident “might is right” worldview. But it doesn’t have to be this way - we can embrace our shared humanity while still competing on the global stage for talent.

in the sunset they do their own fiber

I appreciate apps that provide a universal keyboard shortcut like Zoom that works even if I’m focused on another app. Next best is Google Meet but it only works when you’re focused on the same tab. Worst is Teams, WebEx etc that don’t provide any keyboard shortcut

My mute preference in videoconference tools:

Universal keyboard shortcut > app focused keyboard shortcut > no keyboard shortcut

You only need to look at cultures like in India, Taiwan and elsewhere that have large vegetarian population to see that your statement doesn’t hold water.

LSD helped me give up nicotine and consuming animal flesh. It was very clear to me that I didn’t need either in my life. Why harm myself or other beings for such mundane pleasure when I could now access the transcendent (now through meditation).

Slightly off topic but do Indians generally find Westerners doing Yoga cultural appropriation when it’s stripped from its original context? I actually see Yoga and Hinduism more broadly like open source software with its many philosophies as branches. As such developing a free app is in the same spirit of making (formerly) esoteric practices more accessible

Another perspective is to look at traditional use of opiates in cultures before they were illegal. Raw opium has a much higher ratio of lethal dose to effective dose vs heroin. For example in parts of India elderly will take some opium with their chai to ease the discomforts of old age. While you may become addicted it’s unlikely you will overdose.

A big part of the potency of recreational drugs is due to its illegality forcing suppliers to pack as much of a punch in the smallest package. Another contributing factor is Western culture - you don’t see a huge demand for low potency cannabis. People like their drugs strong.

Looks interesting. What’s your pricing model?