3,581 karma · joined February 4, 2016
> So it works. But there has got to be a simpler/better/non-toxic way to create an ion trap using proteins and make plants work better ...
I remember reading about designed minimal photosystem-like systems. I cannot find the actual paper now, though.
Structure is determined by sequence, so they are equally important. Structure is more conserved than sequence, mainly due to the physicochemical constraints that govern protein folding.
> that "reaction centers" are what matter, and the rest is just "protection"?
Sometimes not even protection. Many enzymes can have plenty of its sequence/structure removed and still be functional. Natural proteins carry lots of evolutionary cruft.
> What do you mean by "reaction center" - surely not physically central within the folded structure
I think they borrowed the term from photosystems/photosynthesis. But, to be more precise, what they actually meant is the active site of an enzyme; the location where the catalyzed reaction takes place.
> (isn't it the surface shape that determines reactivity) ?
Shape is not enough, the chemical nature of the amino acid residues involved is also important. A single mutation in a key catalytic residue will shut down the enzyme even if the shape stays the same.
―François Jacob, “Evolution and Tinkering” (https://web.mit.edu/~tkonkle/www/BrainEvolution/Meeting9/Jac...)
Then you’re one of today’s lucky 10,000. Any time!
(https://doom.fandom.com/wiki/Repercussions_of_Evil#The_Story...)
> He has been playing mahjong since junior high school days, and admitted that though he has rarely lost a game when he was in school, his current level of ability is average. According to him, he has "tournament luck" and has even won mahjong tournaments between mahjong manga artists. He has also participated in professional mahjong matches. He played about two games against Akagi and Kaiji's voice actor Masato Hagiwara, who is known as one of the best mahjong players in the entertainment industry, and made Hagiwara say "I don't think I can beat him."
That version (Club Mate Zero) is hard to get in supermarkets as well, at least where I’m living in Germany. I usually order it online.
Look for “mate cocido”. La Tranquera is the brand I use.