This means that you will need around 10GB of memory when serving 10000 request, while an event based app can serve the same amount of requests with minimal memory.
You also have to take into account that thread creation and context switching is really an expensive operation (contrary what the OP is saying), so the thread-per-request app is adequate only for serving small number of requests but for large numbers you will need to use the event-based approach.
You might get along with a threadpool based approach, but take into account that if your protocol is not stateless, then you will need shared state which means you have to use concurrent data structures, which might complicate code.