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DantesKite

3,802 karma · joined February 22, 2019

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DantesKite··on Emmett Shear becomes interim OpenAI CEO as Altman talks break down
Andrej Karpathy literally just tweeted the nuclear radiation emoji lol.
DantesKite··on U.S. agency declares 21 species now extinct
I'm curious what would be an optimal measure of biodiversity.

As in, if certain species decreases, but another increase, it's not clear to me one is more bad than another.

Obviously, wouldn't want entire ecosystems wiped out. I'm just curious what a good measurement of ecosystem health would be.

I'm sure there's one out there hopefully, as technology advances, we'll be able to mitigate the effects we have on the environment, and occasionally, maybe even help it.

DantesKite··on Ask HN: What Is Your Take on Stephen Wolfram's "A New Kind of Science"?
I like it.

It made me realize why structures in biology might arise in very short time spans "fully formed" as opposed to the the relatively slow process of natural selection (which is an important part of the evolutionary process, but strikes me as insufficient given the short time scales at play).

It makes sense if simple rules can create complex structures. Then it would just be a matter of "exploring" this universe of complex structures which would likely produce this wild assortment of distinct organisms, gradually shaped and refined over time.

I don't think it's the full picture, but it adds an interesting perspective I never considered before.

DantesKite··on Ask HN: What is your experience with Nano-Hydroxyapatite toothpaste?
Bulk Supplements, but mostly because they're the cheapest per gram I can find. I don't think you need anything fancy per se.
DantesKite··on Ask HN: What is your experience with Nano-Hydroxyapatite toothpaste?
Lots of Vitamin D and Vitamin K2 removed most if not all of my tooth sensitivity over the course of a month.

About 5 normal Vitamin D pills every few days so.

I was trying to treat something else out of desperation and noticed my tooth sensitivity more or less vanished.

Which makes sense when considering their role.

But as always, n=1.

DantesKite··on Making Hard Things Easy
On a side note, I use GPT-4 to help me create simple Bash scripts. Haven't run into a problem yet, but I double/triple check they won't do anything strange and most of the time, it works quite well.

Don't understand the script, but this is only for personal use. I wouldn't do the same in a work setting (obviously).

And in this specific example, it's been quite a powerful tool to make many parts of my life easier.

DantesKite··on My solopreneur story
Since when did financial success invalidate technical expertise?
DantesKite··on My solopreneur story
So much envy.
DantesKite··on The Lindy Effect
> One implication is that even things which are becoming less robust over time can display the Lindy effect.

Interesting. And somewhat counterintuitive.

DantesKite··on Beer is great for gut health?
“ Conflict of interest statement

CZ and SH were employed by Tsingtao Brewery Co. Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.”

From the study:

https://pubmed.ncbi.nlm.nih.gov/37560062/

DantesKite··on Turns out lowly thymus may be saving your life
There's an amino acid chain synthesized from the thymus of a cow that helped double my lymphocytes (they were low for months). Called Thymic Protein-A. Readily accessible. One of the few things that made a change. Nothing else really helped me out.

What I find interesting how the thymus becomes essentially a blog of fat as we get older and partially explains why infections tend to hit us harder as we age.

DantesKite··on ChatGPT loses users for first time, shaking faith in AI revolution
In a tweet, the account for Similar Web said they don't actually measure iOS app traffic. They just measure traffic to the specific URL (https://chat.openai.com/).

Tweets in question:

"This chart doesn't measure app usage, only traffic to the website on desktop and mobile." https://twitter.com/Similarweb/status/1676576445764624385?s=...

"The graph indeed shows traffic only to the specific URL, http://chat.openai.com. It should be reviewed in this context." https://twitter.com/Similarweb/status/1676573510490046467?s=...

If you notice the app came out in May 2023 and traffic decreases for the first time in the following month in June 2023.

Additionally, you may notice the tweets refer to a specific chart, which might give the impression if you go on the site, they have the actual data, but this is not so.

As of July 7, 2023, Similar Web can't measure iOS app usage. Only their relative ranking on the App Store which doesn't tell you much about daily traffic usage, although we might be able to infer some patterns.

"Usage data is currently available only for apps in Google Play Store. We're working hard to support iOS apps soon"

https://www.similarweb.com/app/app-store/6448311069/statisti...

Additionally, the article has this to say, which might also give a false impression:

> Downloads of the bot’s iPhone app, which launched in May, have also steadily fallen since peaking in early June, according to data from Sensor Tower.

Downloads isn't the same as traffic. Once you've downloaded an app, you don't generally delete it, then download it over and over again. You just use it and that isn't being measured. Although I would expect traffic usage to slow down or decrease somewhat as downloads decrease as well. I just think there are other factors playing a role here as well that aren't being documented.

Growth can't happen forever and it may be that it's slowed down considerably, but it's also possible the decrease is due to users switching the platform they use to access ChatGPT. As it stands, it's not clear from the data from what I've seen. It may be that users switched en masse to the iOS app or something else entirely.

Would need more data to clarify and confirm.

Also, what the heck is up with this tagline for their newsletter? It sounds so adversarial.

"Tech is not your friend. We are. Sign up for The Tech Friend newsletter."

DantesKite··on XGen-7B, a new 7B foundational model trained on up to 8K length for 1.5T tokens
If you’re curious, you can check the progress of many open source LLM’s and how they perform on various evals here:

https://huggingface.co/spaces/HuggingFaceH4/open_llm_leaderb...

DantesKite··on Show HN: PFAS.report – Measure the forever chemicals in your blood via Quest
This is really cool.

Just being able to take blood tests in general to get a better sense of what might be going on can be so informative.

DantesKite··on Cookie Clicker saved my PhD
> Maybe JavaScript is actually what saved your PHD, although cookie clicker was what pointed you in that direction.

Yes the article strongly implies this with some added nuance:

> I’m extremely grateful to Cookie Clicker for the journey it put me on, but even if I hadn’t ended up learning JavaScript because of it, I still wouldn’t regret, and would cherish, the many many hours I spent tinkering and clicking away in my college dorm bedroom.

DantesKite··on Humans aren’t mentally ready for an AI-saturated ‘post-truth world’
Humans are like that too.
DantesKite··on Ask HN: Dating app thirst-trapping non-premium users ethical?
This reminds me of an observation I had: I think a lot of the best dating apps aren't strictly dating apps.

For example, you'd be surprised at the number of people who have met on Twitter. It's quite a lot.

Even John Carmack recently met his significant other on there following his divorce.

https://twitter.com/ID_AA_Carmack/status/1530022920130543630...

DantesKite··on What Reddit Got Wrong
It's not clear to me the Reddit users will be permanently gone either, unless there's some place like Reddit taking in a lot more users right now.

But I haven't heard of any place like that so far. No real competitor for users to jump ship towards.

DantesKite··on Reddit Strike Has Started
This would work better if there was a viable competitor to Reddit.

As it stands, there doesn't seem to be anywhere for these people to go, so they'll likely come back after a few days. Habits are hard to break.

Habits are a moat too.

DantesKite··on Ask HN: How to organize archived webpages locally?
You should try OpenAI embeddings. They're fairly cheap to run over a large amount of text (should cost <$10 if you have thousands of documents I believe, but correct me if I wrong).

Then you can run searches for content even if the exact words aren't the same.

Like let's say you have a document titled "Measuring canine tooth caries over 2004-2020" and it never once mentions the word "dog".

If you type in "dog" after doing the embeddings, it'll suggest that specific document because "canine" and "dog" are closely related.

Great way to organize large groups of texts, there's plenty of YouTube videos on how to do it, and best of all, you don't have to spend time manually organizing everything. You just let the machine model do it for you.

You could even get it to auto-tag your documents based on what it thinks is the best category for the document and make it easier for you to parse that way as well.

DantesKite··on Ask HN: How do you keep yourself interested in coding as a career?
Side projects can be invigorating if you can find something you've always wanted to build.

I know GPT-4 in particular has made exploring new, small projects fairly easy.

You could do something similar. Mix up the tediousness of doing the same thing day after day. Or find ways to automate certain portions of your work, if possible. I always get a kick out of that.

Or talk to your boss and explain the problem. You could explore switching things up a bit. That's always an option as well.

DantesKite··on Our model suggests that global deaths remain 5% above pre-Covid forecasts
One of the things that isn’t talked about enough in a reasonable and calm way is the impact COVID can have on the immune system long term.

It’s talked about in terms of Long COVID and whether or not it’s psychosomatic, the policies made during the lockdowns, and so forth, but always with so much emotion, and sometimes for good reason. I don’t want to dismiss that or trivialize it. Those are important topics to discuss for how we’ll handle future pandemics.

But the evidence is accumulating that COVID does seem to impact CD8+ T cells, causing T cell exhaustion and reduced effector response. One running hypothesis is that the impaired immune response is caused by a persistent viral reservoir infection, particularly in the gut (although not all people show signs of a spike protein months after the initial infection) causing your CD8+ T cells to express more inhibitory receptors (similar to what happens in HIV or cancer with excessive and prolonged exposure to cancer cells).

Another hypothesis that is lesser known but I find particularly compelling is gut dysbiosis following a COVID infection causing a persistent immune activation that leads to T cell exhaustion or impaired T cell functionality especially through persistent activation of the dendritic cells (which are important for presenting antigens to the adaptive immune systems (i.e. T cells, B cells, etc)).

I think a researcher put it best when they said COVID is roughly halfway between HIV and the common cold in terms of the impact it has on the immune system. It may also not be accurate. We have to find out.

For context, think about how long it took to realize the Epstein Barr virus was a causal factor in multiple sclerosis. It took years of evidence collecting and data analysis to eliminate other confounding variables.

We shouldn’t rush to judgement or a narrative, but remain calm and dispassionate here and examine what’s going on, both for the virus, the vaccine, and the actions taken during the pandemic. It’s important we get it right.

DantesKite··on Everything you always wanted to know about mathematics (2013) [pdf]
Tempted to train a small language model on this text and see what happens lol.
DantesKite··on Same Stop: Life after 26 years as a programmer for Apple
I like that it seems like he optimized the game for the Steam Deck.
DantesKite··on Ask HN: Has journaling improved your life?
It's given me a place to understand problems I might not have otherwise solved or been aware of.

It's a bit like being given a piece of paper to solve math problems, instead of trying to do it all in your head.

Makes a huge difference.

DantesKite··on How are you folks using ChatGPT in your daily life(except work)?
I ask it sometimes whether or not it can automate a common workflow I do on the computer and it'll occasionally surprise me with something I didn't know existed.

Like being able to do rule-based sentiment detection analysis and injecting that code into my browser, so I only see neutral/positive comments on Hacker News instead of the usual cynical takes lol.

DantesKite··on Exercise increases number of immune cells in cancer patients
Makes sense.

Metabolic processes and immune pathways are closely interlinked together (such as through the mTOR pathway).

Activate mTOR and you get the signal for T cells to proliferate as well as muscle growth, especially in the context of hypertrophy.

DantesKite··on The Struggle to Make Lab-Grown Meat
I've always wanted lab-grown meat.

Not the kind that looks like sludge, but the kind that would be indistinguishable from a beef patty you buy at the store, not least because it would be a more efficient way of producing food at scale.

But also because some of that technology would also eventually be applied to the creation of human organs.

And I'd like to live in a world where the waiting list for an organ transplant is just a few hours for everybody.

DantesKite··on Everyone with blue eyes may descend from a single human ancestor
Another take I’ve heard is that lighter eyes allow you to see the dark ring around the iris (limbic rings), which apparently fades as you age, becoming progressively lighter, forming a sort of proxy for age.
DantesKite··on Apple will launch a journaling app
I wonder if they’ll use this to train large language models.
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