HN is going to hate me for saying this, but there's another problem besides your actual skillset. At least in the start-up bay area scene, working 10 years at a big company[1] absolute is a negative to a bunch of people because they __assume__ you won't be a good culture fit.
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1. Not talking about the Facebook/Apple/Google trendy companies. I'm talking of Wells Fargo, JCPenny's and at&t.