I got to the same point a few years back.. so I quit my job, sold all my stuff and drove a $6000 Jeep Wrangler from Alaska to Argentina for 2 years. [1]
I've just been back at a desk for 4 years, but am again burnt out so now I quit again, and I'm driving around Africa for 2 years starting in a couple of months.
Get out and live, I say!
[1] theroadchoseme.com