Blind Return Oriented Programming [pdf]

I'm by no means an expert on binary exploitation, so I don't feel qualified to answer your question. That being said, SafeStack sounds very similar to a fairly recent exploit mitigation technique known as heap partitioning, or heap isolation. My explanation wouldn't do the concept justice, but Google recently wrote a great article on how they're using the technique to eliminate some of the biggest causes of Flash 0day [1]. I don't know how effective the technique is in practice, but it seems to be in use by a few major browsers now, and it seems like Internet Explorer has been using it since June of last year [2].

[1] http://googleprojectzero.blogspot.com/2015/07/significant-fl...

[2] https://labs.mwrinfosecurity.com/blog/2014/06/20/isolated-he...