Note: CTRL-S does not work on all terminals and might block further input, use CTRL-Q to get going again.
http://vim.wikia.com/wiki/Map_Ctrl-S_to_save_current_or_new_...
(Caveat emptor, can't speak from first hand experience.)
We had a discussion a few days ago about the ways in which some interfaces (command line in particular) can be user-hostile. (https://news.ycombinator.com/item?id=9831429) Vim's Ctrl-S appears to be a function, keyboard-adjacent to several commonly-used functions, whose main effect for many users is "cause the program to fail immediately with no indication of how to fix it." I don't think I could make up a better example of user-hostile design if I tried.
I have only experienced a handful of vim crashes but all of them were caused by plugins.
Microsoft Word doesn't even accept patches, which I do indeed hold against it.