As others pointed out, Tesseract with OpenCV (for identifying and cropping the text region) is quite effective. On top of that, Tesseract is fully trainable with custom fonts.

In our use case, we've mostly had to deal with handwritten text and that's where none of them really did well. Your next best bet would be to use HoG(Histogram of oriented gradients) along with SVMs. OpenCV has really good implementations of both.

Even then, we've had to write extra heuristics to disambiguate between 2 and z and s and 5 etc. That was too much work and a lot of if-else. We're currently putting in our efforts on CNNs(Convolutional Neural Networks). As a start, you can look at Torch or Caffe.