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Ageing has several causes, including the accumulation of clutter (basically poison) inside and outside of our cells. I'm not sure becoming a vampire is enough to overcome that.

Given the uncertainties, I'd still want to keep cryonics as a back up. (Though it looks unavailable here in Western Europe.)

The wear and tear theory of aging is just one of many currently popular, the body is not a mechanical machine necessarily bound to wear and tear, it can in some cases successfully heal itself, some species basically don't age (some can actually revert in lifecycles).

A competing theory is programmed aging (in which "clutter" would be an effect of, not a cause): http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1369273/

Any idea if that Ray Kurzwiel guy is doing young blood transfusion? It sounds like it would fit his goals as an early adopter of life extension tech..

Do you have a recommended reading list?

Just off the top of my my head: https://en.wikipedia.org/wiki/DRACO_%28antiviral%29 CRISPR as mentioned, anything nano(robotics, surgery etc.), as well as stem cell tech.