My solution: 3 security tiers:

high (email, banking): Just memorize a unique password for each

medium (sites that might have my credit card info): Lastpass + salt, which I memorize and manually insert (last pass doesn't have it)

low (everything else, e.g. hacker news): I trust lastpass (w/ 2f) for these sites.

I feel that this strikes a good balance between security and convenience for me, without putting too much trust in the central store. I don't think LastPass is the weak point in this system (I am).