To test this, we would get a mouse line, which are genetically very similar to each other from inbreeding so we won't have to worry about rejection of the transplants, and introduce the human CCR5 receptor into them. This, in theory, will allow the mice to be infected with HIV since HIV attaches to the CCR 5 receptor to enter and infect the cell. If this works, we can then try the technique of taking some of their stem cells, introducing the mutation, transplanting them back in, and see if their T cell count increases or if the levels of HIV decrease. It could also be used as a preventative therapy, which we can also easily test on the mice.
Personally, my error medication invention will be a contribution I'd like to make to patients and to my profession. You don't get second chances when you deal with patients.. a first error can kill.
Each time I get an episode of it I can't help but wonder why it is that much harder to find a cure for it than fixing a broken computer:) May be I can use this innocence and get somewhere. Medicine is the last thing of my natural interest but in this context I really hope to take on this fun challenge at some point.
No patents.
I already more-or-less solved the first round of problems in doing affordable housing for the developing word:
http://Appropedia.org/Hexayurt_Project - and placed all that work into the public domain. So now it's time to hunt bigger fish.
Reality is much, much clearer if you think about the needs of the very, very poor, and the interaction between the shocking arrival of the cellphone and solar panels or the national grid and the basal economic needs of a family.
Got the contract from the Federal Govt. to write the papers and prepare a demo of the technology coming next week I'm told, and it'll be going into the public domain shortly thereafter.
To encourage people to do this, you could build a game like this:
In a sense, this "first impressions" service would also provide a form of advertising targeted at people who are willing to see what you have just for fun.
- political social network (get people talking)
- revolutionize the structure of the internet (its a mess)
- introduce new airline software (I'd sell that myself)
If anyone wants to do any of these things feel free, because they need to be done. If you want to participate in my efforts to seem them happen in the future - maurice@revvu.com
I'm sure it would be nearly impossible to sell. ;-) Hence i volunteer to sell it myself. I'm sure it would be a huge undertaking because of things the hardware limitations & time it would take to update things... but once in place, it'd be well worth it for everyone involved.
I'm also not particularly interested in P2P payments, as there are lots and lots of systems out there for that, and it never has really taken off. The dominant system is still merchant/customer, and I think it will continue to be for a number of reasons: each person receiving payments needs a lot of people paying to make any given activity worth doing, and people just don't seem to pay each other tiny sums -- and paycheck-size sums are already handled well by check/ACH, direct deposit, and so on.
But given the level of funding I'll need to get this started properly, it certainly isn't a YC app, so I have to succeed with some other interesting project first. :)
perhaps we can cook up something!
-deaf people communicate without sign language.
I already have the ideas - but no prototype. would need funding.
:)
But to your point, I meant that cultures do change; willingly or unwillingly, when faced with disruptive and effective technology. The strange thing is; they sometimes willingly change for the worse.