Roll your own using Katana? Yeah that'll work but consider just using http://nancyfx.org/ or if you need something more structured https://servicestack.net/ | http://www.asp.net/web-api
Katana/OWIN provides a pipeline for hosting .NET web[sites|services] without IIS. This is another direction .NET is heading, no more IIS shackling (if you so choose)
Plus, no need to rely on Powershell scripts, or god forbid, the user, to get the correct set of IIS features installed has made deployment of our apps infinitely simpler.