I'm not saying this would happen
tomorrow. Microsoft has enough inertia to fire all their developers and just sell the current version of Windows and Office for a
long time. Hell, some 30% of computer users in China still use
Windows XP.
After a few generations raised on smartphones and tablets without any Microsoft apps, Microsoft Office would just be a curiosity their parents used, like Corel Draw or dBase.
Fortunately Microsoft has taken note; there's rumor of Android Office apps, and the latest version of the Surface tablet is quite popular.
Microsoft, and in particular, Office is still going strong, but the stranglehold it had in the 90's is gone.
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Google may want businesses to pay, but going to docs.google.com and using your personal email address works just fine - much to the chagrin of IT departments everywhere.