The westernized aspect has absolutely nothing to do with having an impact or not. The east / west thing is bullshit, nothing more. If someone tells you that you can't have an impact because of western culture, they're merely looking to prey on naivety or ignorance to further their own irrational agenda or bias.
To have a meaningful impact, you need a platform / vehicle. It's what all people have in common that have made a positive difference throughout history.
You can do it by inventing something new that makes life better (easier, healthier, more fulfilling, etc). Imagine how much time and effort things like refrigeration save us today, and how much better that makes ~2 billion lives. If you save someone an hour per day with an invention like that, you've just given them more life in real terms - time with their children, time in which they can make a difference, or just spare them hardship.
You can make a lot of money and put that to good use. Even though it's a wildly unpopular thing to say, Bill Gates will have a drastically greater positive impact on the welfare of humanity than Mother Teresa (or people like that). Drastically is understating things too much.
You can - try - to make a difference through politics. This is extraordinarily challenging, and can usually only have maximum impact at times of desperation and chaos. That's when people are open to new messages (good or bad).
You can make your platform an idea. Whether that's civil rights, or universal suffrage, or liberty, or privacy, etc. Then you have to choose how to go about furthering it, whether through an organization, or writing on your own, or a dozen other options.
Bottom line, you must have a lever. Your platform / vehicle is at its core a system of leverage, ideally. Meaning, it's something that other people too will care about, because it's important. If it is, then they will contribute energy into amplifying the reach and impact of that platform. You don't get very far on your own, build systems that other people will get behind and readily lift higher.