I had always wanted and expected to achieve great things. I think this is a natural and healthy desire. But when I looked back on the last 10 years I realized I wanted to be a political figure (when I was left wing) then a famous scientist, then a famous scientist in another field, etc. The only common thread was the desire to be great and to have a big (positive) impact on the world.
To let go of this required me to realize that a small probability of having a big impact on the world was not better than the certainty of having a small impact. Once I was open to making a small impact, it became very easy to see the value in my work, and to focus on enjoying the fortunate position of having an easy job that paid well.