I just crashed a 2008 R2 server without a rule, just with "Enable Kernel Caching".
Not sure if it is relevant, but I first added a rule for .png, and then removed it again. Still worked.
If you can't afford to reboot your servers right now to install the patch, at least you can add this to your web.config and deploy your websites ASAP :
<configuration> <system.webServer> <caching enableKernelCache="false"/> </system.webServer> </configuration>
EDIT:
It causes a config error when a lock violation occurs which means the site gets an error 500 so its not an ideal fix.