Replacing $100K diagnostic chip fab with Shrinky-Dinks and a laser-printer
boingboing.net
boingboing.net
http://en.wikipedia.org/wiki/Microfluidics
http://en.wikipedia.org/wiki/Shrinky_Dinks
http://en.wikipedia.org/wiki/Shrinky_Dinks
Seems like you would be able to get pretty small feature sizes if you had a really high resolution printer to begin with...
If the ability to form troughs/ridges is the important thing then I think that the PCB etch/make mold technique would be just as useful. But I'm not sure what the smallest feature size is that you can make with this method:
PCB etch/make mold method:
Laser-print an inverse pattern mask on clear plastic film
Expose a UV sensitive photoresist PCB using the mask
Etch the PCB
Make a polymer mold (or mold the final part) using the troughs/ridges formed by the etched/unetched copper on the PCB
I know this method has been used for replicating fingerprint patterns in the past (Mythbusters!) and I remember hearing it being used for a few other things...
(It drives me nuts that when people downvote you, but don't give an explanation)
Given your karma and how long you've been here, you should know better! FOR SHAME!