Early-stage theories
blog.tlb.org
blog.tlb.org
a) You're a reclusive genius dedicating your life to solving in secrecy a problem many hundreds of years old; or
b) You're afraid to find out that what you've been working on was stupid.
Guess which one is more likely?
I totally agree that experimentation can lead you to insights that no one else has had - that no one else can have without it, but which are plain once you've played with a prototype. It doesn't mean you're more perspicacious, it's just that standing on a hill, it's easy to see more. Climb a few hills that no one else has, and you have a unique perspective.
I can't think of many technologically disruptive YC start-ups off the top of my head to be honest.
However, I've been told that there are several technology-based ones, but they haven't launched yet because they're working on the technology. We tend to hear about the other ones.
ps - the list of questions is cool.
edit: wait is "email" the answer? the comparison to flying machines still blows my mind. eit.