Sencha gets a lot of flak, but IMO it is the most mature, built out framework you can get. You get, out of the box:

1. MVC/MVVM structuring

2. a DOM abstraction, which albeit requiring a lot of learning, works once you grok how to use it (something that can only unfortunately come with experience)

3. Touch driven gestures

4. History and repetitive task management

5. A grid view that's unparalleled in the market.

And that's just for starters. It's downsides include a steep learning curve and a classical inheritance model, but those should hardly be blockers to anyone willing to invest the time it demands.