We have beta SDK's available for Python[0] and Ruby[1]. There are free test listings available if you're interested in trying it out (no signup required).
My brother and I co-founded SimplyRETS earlier this year to solve the real estate industry's archaic data problem. We built a modern, RESTful API in Haskell that normalizes MLS data and makes it easier for developers to build websites and applications.
We'd love to hear your thoughts and feedback!
[0] - https://github.com/SimplyRETS/simplyrets-python-sdk [1] - https://github.com/SimplyRETS/simplyrets-ruby-sdk