I switched from a Line6 PodXT to a Fender DeVille. I actually prefer less options, since I'm now no longer paralyzed by choice. The tube amp sounds much better than anything I got out of my Pod.
Having said that, the amp wants to be loud in order to hit the sweet spot, but it's already screaming with the volume at 3. I can't really get it to the optimal place without blowing everyone else off stage. Also, I never thought I was going to hurt my back hauling the Pod up a flight of stairs. I wouldn't go back, though.