The drug cartels brutally murder thousands and commit many other crimes -- they are as brutal as ISIS in many ways -- they undermine and oppress entire countries and ruin large parts of American cities. Many organizations such as the Taliban and Hezbollah fund themselves via the drug trade.
Some people boycott companies over political issues; how many of them still buy drugs? Every user I know, to whom I've mentioned this issue, insists their drugs come from a friend who produces it at home. But somehow the drug cartels earn billions and have worldwide distribution networks.