I can see to not allow connections to be made to any host in the local network. That's fine. But blocking access to the loopback interface is IMHO going a bit too far as this was until now a very portable and secure way for websites to talk to locally installed helper applications.
Dropbox does this, Github for Mac does this (and incidentally, my own home-grown solution for reading barcode scanners does this too).
I really don't want to have to end up in a world where we have to write browser-specific solutions (the method recommended in the issue is chrome-specific) for these kind of things.