I assume mansr refers to profile guided optimizations in gcc and many other compilers. See http://en.wikipedia.org/wiki/Profile-guided_optimization.

GCC has supported `-fprofile-generate` and `-fprofile-use` for profile-guided optimization since (at least[1]) GCC 3.4, which was released over 10 years ago:

https://gcc.gnu.org/onlinedocs/gcc-3.4.0/gcc/Optimize-Option...

Firefox is an example of an application that ships production binaries with PGO.

[1] It was actually supported earlier than this, but I didn't search further; the 3.4.0 manual says "New -fprofile-generate and -fprofile-use command-line options to simplify the use of profile feedback", implying it was there before in a less convenient form.

Or rather, "I may be mistaken in my grand assertion, but I'll place the burden of proof on you".