I have only briefly checked out this library so take what I say with a grain of salt, but from what it looks like we had a very similar implementation to this on the project i'm currently involved with, also very inspired by Om.
At first it worked out great for us but as our application grew both in scope and number of developers involved, we quickly ended up with a 'cursor soup' where too many components were watching for changes individually.
It had a very negative impact on performance since components would potentially re-render multiple times for a single change. In our last implementation we ended up overcoming this by some fancy event consolidation, but even so we had too many components 'touching' our tree.
We ended up reverting to a much simpler architecture and it has both made our application dumber (which is great in terms of maintenance) but also more performant. We currently have actions/stores/views where actions themselves are dispatchers. By creating a few helper functions we overcome a large part of the boilerplate but even without, it has proved worth it for us.