No, not at all. Every once in a while there’s an extremely bad storm that makes it difficult, but for the most part the infrastructure (plows, salt trucks, etc.) has adapted to the climate such that it’s not a problem 97% of the time.
Minnesotan here, everyone in my office takes their laptops home if we think it'll snow. If it snows during the commute then things slow down, but there's armies of plow trucks and things get cleared quickly.