Every serious application, regardless of their resume, got a 30-45 minute phone call. You post hiring posts all over the place and you get a lot of unserious submissions, but an easy way to screen them out is to respond with a question, like, "Thanks for writing! We'd be happy to talk to you. Can we ask what has you interested in doing software security?" The answer doesn't matter, as long as there is an answer.
I did a lot of calls where I knew a couple minutes in that we were unlikely to hire the person, but (a) I got surprised by outcomes enough not to shirk on those calls, and (b) those calls are a very small price to pay for finding buried talent.