I feel this problem is especially significant in San Francisco. Having lived in several other cities, I can say that, at least for me, this was never a major issue before living in SF. Meeting other programmers and people in tech out in the real world used to be a pleasant surprise. Now it's just a given.

Coffee shops, climbing gyms, museum nights, hiking meet ups, hanging out in the park, etc etc... I, like apparently every other person in tech, enjoy these things. I do miss the diversity of thoughts and lifestyles to be found in other cities. Not that SF doesn't have such diversity, it's just that I never before had to make an effort to find it outside my normal activities.