Optimizing for large scale production is indeed what most of the field works on. There have been many success stories: an anti-malarial drug through yeast (Artemisinin by Amyris+Sanofi), a plastic precursor through bacteria (1,4-BDO by Genomatica+DuPont), and more.

What they are missing is the whole spectrum of what could be made biologically. We will create microbes for the most valuable chemicals and then partner with existing optimization companies that have industrial fermenters running. Think beer fermentation, just instead of the alcohol yeast, you use our yeast.