Sure, if you hate your job, or it's meaningless. But let's turn this around. Do great painters wish they had spent less time painting? Or do they wish they could finish their last project. Do writers wish they had written less, or do they wish they could live long enough to finish that last book?
I do what I do because I enjoy doing it more than spending time with my family. For better or for worse, it is a compulsion, a calling, not a job.