Ask HN: What resume projects would you like to see?

I just got laid off, and have two years' experience as a software engineer (mainly python and JavaScript, but others as necessary). I don't have a CS degree, and my portfolio only includes little JavaScript doodads that don't illustrate a wide range of skills. What kinds of projects should I work on adding to my portfolio? Should I stick with Python where I'm comfortable, or start learning Rails or something else? I'm looking for full-stack and front-end positions.